Clik here to view.
“Straightforward and Versatile Synthesis of Fullerooxazoles from C60 and...
“Straightforward and Versatile Synthesis of Fullerooxazoles from C60 and Carboxamides through Radical Reactions under Mild Conditions” Youhei Takeda, Satoru Enokijima, Toshiki Nagamachi, Kazuhisa...
View ArticleClik here to view.
trans-Clerodane natural product synthesis
Originally posted on Naturalproductman's Blog: Larry Overman and co-workers have reported in JACS on the synthesis of trans-clerodane natural products. JACS paper View original
View ArticleClik here to view.
Structure property calculation in apps: MMDS
Originally posted on Cheminformatics 2.0: An important milestone in has been reached in the migration of complicated structure-based calculations to pure mobile. The latest version of MMDS (1.5.9) is...
View ArticleClik here to view.
Logistics of process R&D: transforming laboratory methods to manufacturing scale
Originally posted on New Drug Approvals: The manufacture of a | omeprazole (racemic product; top), and esomeprazole (the (S)-enantiomer; bottom), including b | a flow chart of the process for the …...
View ArticleClik here to view.
Two-Step Cyanomethylation Protocol: Convenient Access to Functionalized Aryl-...
Two-Step Cyanomethylation Protocol: Convenient Access to Functionalized Aryl- and Heteroarylacetonitriles Peter J. Lindsay-Scott *, Aimee Clarke , and Jeffery Richardson Eli Lilly and Company Limited,...
View ArticleClik here to view.
A Novel and Practical Synthesis of Ramelteon
Originally posted on New Drug Approvals: RAMELTEON An efficient and practical process for the synthesis of ramelteon 1, a sedative-hypnotic, is described. Highlights in this synthesis are the usage of...
View ArticleClik here to view.
Route Design in the 21st Century: The ICSYNTH Software Tool as an Idea...
Originally posted on New Drug Approvals: The new computer-aided synthesis design tool ICSYNTH has been evaluated by comparing its performance in predicting new ideas for route design to that of...
View ArticleClik here to view.
One-pot triangular chemoenzymatic cascades for the syntheses of chiral...
One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine Green Chem., 2015, 17,852-855 DOI: 10.1039/C4GC02325K, Communication B. R. Lichman,a E. D. Lamming,b...
View ArticleClik here to view.
5 lakh plus views on New Drug Approvals blog
FLAGS AND HITS MYSELF DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the...
View ArticleClik here to view.
7-allyl-6-hydroxy-indan-1-one…Mom will teach you NMR
Thermal Claisen rearrangement on 6-allyloxy-indan-1-one, (III) to obtain 7-allyl-6-hydroxy-indan-1-one, (IV): Formula: C12H12O2 Molecular Weight: 188.22200 Synonyms:...
View ArticleClik here to view.
CS 3150, angiotensin II receptor antagonist, for the treatment or prevention...
Originally posted on New Drug Approvals: CS-3150, (XL550) CS 3150, angiotensin II receptor antagonist, for the treatment or prevention of such hypertension and heart disease similar to olmesartan ,...
View ArticleClik here to view.
OFLOXACIN
Originally posted on New Drug Approvals: OFLOXACIN Molecular Formula: C18H20FN3O4; (Formula Weight: 361.37; mp: 270-275°C; Ofloxacin is one kind of white or almost powder or off-white solid. The...
View ArticleClik here to view.
XMDS: progress toward structure sketcher
Originally posted on Cheminformatics 2.0: Since the last sneak preview, the skunkworks project “XMDS” – the Mac OS X desktop version of the Mobile Molecular DataSheet app – has gained enough...
View ArticleClik here to view.
C-H activation with Pd
Originally posted on Naturalproductman's Blog: Erik Alexanian and co-workers have reported in JACS on a palladium catalyzed C-H arylation from alkyl halides.JACS paper View original
View ArticleClik here to view.
Retosiban, GSK221149A
Originally posted on New Drug Approvals: Retosiban, GSK221149A 820957-38-8 MW 494.5827, MF C27 H34 N4 O5 Oxytocin antagonist Threatened pre-term labour PHASE 3 GSK UNII-GIE06H28OX, GSK 221149A,...
View ArticleClik here to view.
How to leave a strong impression
Originally posted on Org Prep Daily: I got a summer internship in a natural product synthetic group, a quarter century ago when I was in high school. It was a very nice lab, doing medicinal chemistry...
View ArticleClik here to view.
A rant about data quality: machines first, humans second…
Originally posted on Cheminformatics 2.0: Recently one of my papers emerged through the publication system of Journal of Cheminformatics, entitled “Machines first, humans second: on the importance of...
View ArticleClik here to view.
Enzymatic resolution of antidepressant drug precursors in an undergraduate...
EducaçãoQuim. Nova 2015, 38(2), 285-287 Enzymatic resolution of antidepressant drug precursors in an undergraduate laboratory Luís M. R. SolanoI; Nuno M. T. LourençoII,* This paper describes a...
View ArticleClik here to view.
Synthesis of 1H-benzoxazine-2,4-diones from heterocyclic anhydrides:...
Quim. Nova 2014, 37(8), 1297-1301 Synthesis of 1H-benzoxazine-2,4-diones from heterocyclic anhydrides: evaluation of antioxidant and antimicrobial activities Juan I. Sarmiento-SánchezI,*; Julio...
View ArticleClik here to view.
An efficient and inexpensive device for undergraduate chemistry classes...
Quim. Nova 2014, 37(1), 164-167, 2014 Um reator fotoquímico barato e eficiente para experimentos de química Ramon Kenned Sousa AlmeidaI; Cláudia MartelliI; Gilson Herbert Magalhães DiasI; Julio Cesar...
View Article