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New “mTOR” inhibitor from Exelixis, Inc., XL 388

Originally posted on New Drug Approvals: XL 388  A Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)...

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Solvent-free Mizoroki–Heck reactions and its application in the synthesis of...

Originally posted on Green Chemistry International: A green method for the synthesis of a D-glucosamine-derived triazole@palladium catalyst is described. The synthesized catalyst containing a...

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Functionalized aryl-β-C-glycoside synthesis by Barbier-type reaction using...

  Kiyomi Ohba, Yuichi Koga, Sumihiro Nomura, and Masaya Nakata “Functionalized aryl-β-C-glycoside synthesis by Barbier-type reaction using 2,4,6-triisopropylphenyllithium” Tetrahedron Letters, 2015,...

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8-Oxo-5-aza-spiro[2.5]octane-5-carboxylic acid benzyl ester,

8-Oxo-5-aza-spiro[2.5]octane-5-carboxylic acid benzyl ester, 1H NMR STR 4 SEE BELOW STRUCTURE5= SEE SYNTHESIS...

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New Drug Approvals blog fast approaching 8 lakh views ( 27/7/2015)

Originally posted on New Drug Approvals: New Drug Approvals blog fast approaching 8 lakh views ( 27/7/2015) 799174 VIEWS IN 208 COUNTRIES View original

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ORGANIC SPECTROSCOPY INTERNATIONAL HAS 2 LAKH VIEWS

Originally posted on New Drug Approvals: ORGANIC SPECTROSCOPY INTERNATIONAL HAS 2 LAKH VIEWS Read by one and all in academics and industry link is ……http://orgspectroscopyint.blogspot.in/ I get...

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ENZALUTAMIDE

Originally posted on New Drug Approvals: Enzalutamide, MDV-3100 MDV3100 is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential...

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A Continuous Flow Chemistry Platform for Low Temperature Reactions

A low temperature reactor platform that facilitates metalation followed by electrophilic quenching, and related reactions under continuous flow-through conditions has been developed. Pre-cooling loops...

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Metal-free synthesis of polysubstituted oxazoles via a decarboxylative...

Scheme 1 Control experiments. The ubiquitous oxazoles have attracted more and more attention in both industrial and academic fields for decades. This interest arises from the fact that a variety of...

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Why I Joined Shoolini University?

Originally posted on Robins1987's Blog: Placed between two bustling cities of Chandigarh and Shimla, Shoolini University lies at the foothills of the Himalayas. Combining three academic fields of the...

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New “mTOR” inhibitor from Exelixis, Inc., XL 388

Originally posted on New Drug Approvals: XL 388  A Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)...

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Iron bis(oxazoline) complexes in asymmetric catalysis

Iron bis(oxazoline) complexes in asymmetric catalysis Asymmetric reactions catalyzed by iron complexes have attracted considerable attention because iron is a ubiquitous, inexpensive, and...

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2-(BENZYLOXYL)-6-ETHYL-2H-PYRAN-4-ONE

2-(BENZYLOXYL)-6-ETHYL-2H-PYRAN-4-ONE   see………http://orgspectroscopyint.blogspot.in/2015/12/6-ethyl-4-hydroxy-2-pyrone.html...

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Zucapsaicin for osteoarthritis

Originally posted on New Drug Approvals: Zucapsaicin (珠卡赛辛) cis-Capsaicin; (Z)-Capsaicin Zucapsaicin; Civamide; Cis-Capsaicin; 25775-90-0; (Z)-Capsaicin;...

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New Drug Approvals hits ten lakh views in 211 countries

New Drug Approvals New Drug Approvals hits ten lakh views in 211 countries http://newdrugapprovals.org/ ////////// View original post

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Fluoxastrobin

Fluoxastrobin Fluoxastrobin Fluoxastrobin; Disarm; Fluoxastrobin [ISO]; UNII-XQ43WY091Y; HEC 480 SC;...

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Simultaneous measurement of multiple heteronuclear coupling constants

NMR Methodologies “Simultaneous determination of the magnitude and the sign of multiple heteronuclear coupling constants in 19F or 31P-containing compounds” by Josep Saurí, Pau Nolis and Teodor...

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WO 2016012938, New patent, LINACLOTIDE, DR. REDDY’S LABORATORIES LIMITED,

New Drug Approvals WO2016012938,  IMPROVED PROCESS FOR PREPARATION OF AMORPHOUS LINACLOTIDE DR. REDDY’S LABORATORIES LIMITED [IN/IN]; 8-2-337, Road No 3, Banjara Hills, Telangana, INDIA Hyderabad...

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PF 04995274, a 5-HT4Partial Agonist

New Drug Approvals PF-04995274, (R)-4-((4-(((4-(Tetrahydrofuran-3-yloxy)-1,2-benzisoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol...

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BENZYL VINYL ETHER

Green Chem., 2016, Advance Article DOI: 10.1039/C5GC02977E, Communication Ryosuke Matake, Yusuke Adachi, Hiroshi Matsubara A convenient preparation of vinyl ethers from alcohols with calcium carbide...

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