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Comparison between microwave to flow technology – tech transfer

Originally posted on Totally Microwave: Although I found an example in the literature in moving from a microwave method to a micro-reactor method – and placed it in my synthflow resource blog, it...

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Microwave to Continuous Flow Tech Transfer

Originally posted on SynthFlow: I’m not sure if it was in the generic scheme of the reactions performed, the authors of the work or the title translating microwave methods to flow that got me: truth...

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Dr. Crasto’s news on Continuous flow for drug synthesis

Originally posted on SynthFlow: As I mentioned in the past week, I will take some time to provide some of Anthony Melvin Crasto’s information of flow approaches to drug discovery and API synthesis —...

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Synthesis of 6-Deoxypladienolide D, which binds to SF3B1

Originally posted on Naturalproductman's Blog: Gregg Keaney and co-workers at H3 Biomedicine have reported in Org Lett on the synthesis of 6-deoxypladienolide D.OL paper View original

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Fish Oil Helps Heal Bed Sores of the Critically Ill

Originally posted on Clinicalnews.org: Tuesday, December 4, 2012 Tel Aviv University research finds a 20-25 percent reduction in pressure ulcers with a fish oil enriched diet Chock-full of Omega-3...

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Flow Chemistry test facility in India

Originally posted on New Drug Approvals: Flow Chemistry test facility in India BOOK YOUR TRIAL on  Plantrix® Industrial system. Contacts:India Vijay Kirpalanivk@pi-inc.co 0091 9821 3420 22 More...

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Alpha-arylation of 3-benzazepin-2-ones with microwave heating

Originally posted on Totally Microwave: I came across an interesting article on alpha arylation of a 3-benzazepin-2-one, which is a particularly sluggish reaction (TL 2013). First thing is first, the...

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Domino 3 Component Microwave: Mannich, Indole formation, N-Arylation

Originally posted on Totally Microwave: I have been reading through cyclocondensations and multi-step routes to fused ring systems and came across a highlight from Doris Dallinger’s post on the...

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[gamma]-Valerolactone as an alternative biomass-derived medium for the...

[gamma]-Valerolactone as an alternative biomass-derived medium for the Sonogashira reaction Green Chem., 2015, Advance Article DOI: 10.1039/C4GC01728E, PaperDOI: 10.1039/C4GC01728E...

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Upgrading of glycerol acetals by thermal catalyst-free transesterification of...

Upgrading of glycerol acetals by thermal catalyst-free transesterification of dialkyl carbonates under continuous-flow conditions Green Chem., 2015, Advance Article DOI: 10.1039/C4GC01750A, Paper...

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Thioalkynes from hypervalent iodine

Originally posted on Naturalproductman's Blog: Jerome Waser and colleagues at EPFL have reported in JACS on a way to synthesize thioalkynes from hypervalent iodine. JACS paper View original

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4-Hydroxycyclopentenones from furans

Originally posted on Naturalproductman's Blog: Javier Read de Alaniz and co-workers from UCSB have reported in Tetrahedron Letters on the synthesis of cyclopentenones from furans through a Piancatelli...

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Drug Patents International

Drug Patents International.

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Dr Andrew L. Lawrence…..Excellent chemistry at work

  http://www.chem.ed.ac.uk/staff/academic-staff/dr-andrew-l-lawrence organic chemistry research group based at the School of Chemistry at the University of Edinburgh in Scotland. Dr Andrew L. Lawrence...

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Syrris announces use of systems in polyketide flow total synthesis

Originally posted on SynthFlow: Fresh out of the Ley group: use of the Syrris system for a strategy in polyketide natural product synthesis, mostly under continuous flow conditions. Highlighted in the...

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Article 0

Originally posted on The Global Innovations: New advancements in catalysis by merging knowledge from catalysis and supramolecular chemistry To read the full story CLICK HERE View original

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Solved NMR Problems: Webspectra Beginner Problem #2

Originally posted on How to Ace Organic Chemistry: This is a continuation of my Solved NMR Problem series, where I solve NMR problems from various databases around the web. See this article for my...

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A rapid, convenient, solventless green approach for the synthesis of oximes...

Originally posted on Green Chemistry International: A rapid, convenient, solventless green approach for the synthesis of oximes using grindstone chemistry Lakhinath Saikia, Jejiron Baruah, Ashim...

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A truly green synthesis of α-aminonitriles via Strecker reaction

Originally posted on Green Chemistry International: A truly green synthesis of α-aminonitriles via Strecker reaction Debasish Bandyopadhyay, Juliana M Velazquez, Bimal K BanikOrganic and Medicinal...

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I did not run away from a NaCN Exotherm

Originally posted on New Drug Approvals: DELTAMETHRIN DID NOT RUN AWAY FROM NACN ie sodium cyanide EXOTHERM ALMOST VIRTUAL ACCIDENT AT RPG LIFESCIENCES (SEARLE) PANOLI GUJARAT INDIA 1999-2000...

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