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Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles as an...
Originally posted on New Drug Approvals: Scheme 1: Synthesis of ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs) using ethanol and pyridine in their reactions....
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Microwave-Assisted Three-Component “Catalyst and Solvent-Free” Green...
Originally posted on Green Chemistry International: Scheme 1: Synthesis of 4H-benzo[b]pyran derivatives under MW irradiation. Microwave-Assisted Three-Component “Catalyst and Solvent-Free” Green...
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Bronsted acid ionic liquid-catalyzed reductive Friedel-Crafts alkylation of...
Green Chem., 2015, Advance Article DOI: 10.1039/C4GC01299B, Communication Amir Taheri, Bingbing Lai, Cheng Cheng, Yanlong Gu C3-cycloalkylated indole was synthesized from indole and cyclic ketone in...
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Combining chemical and enzymatic synthesis
Originally posted on Naturalproductman's Blog: Kevin Reynolds and co-workers from Portland State University have reported in JOC on the synthesis of premarineosin analogs using a chemo-enzymatic...
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Pyridinium leaving group
Originally posted on Naturalproductman's Blog: Philip Albiniak and colleagues at Ball State University have reported in Tetrahedron Letters on the synthesis of tert-butyl ethers using a pyridinium...
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IMPROVED CONTINUOUS FLOW PROCESSING: BENZIMIDAZOLE RING FORMATION VIA...
Improved Continuous Flow Processing: Benzimidazole Ring Formation via Catalytic Hydrogenation of an Aromatic Nitro Compound http://pubs.acs.org/doi/full/10.1021/op400179f Org. Process Res. Dev.,...
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Pi-Process Intensification Experts LLP at CPhI Mumbai India 3rd Dec 2014…My...
Originally posted on New Drug Approvals: I (Dr Anthony) seated with Dr Vijay Kirpalani CEO of Pi-Process Intensification Experts LLP at CPhI Mumbai India 3rd Dec 2014 Pi-Process Intensification...
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At Scientific Update Organic Process Research and Development Conference,...
Originally posted on New Drug Approvals: I am seated left with DR PAUL MURRAY, DR JOHN KNIGHT, DR WILL WATSON, At Scientific Update Organic Process Research and Dev Conference, NCL, PUNE ,INDIA, 5 TH...
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CATALYSIS CONSULTING ………..DR PAUL MURRAY ON A ROLL IN CATALYSIS ARENA
DR PAUL MURRAY LEFTSIDE IN BLACK SUIT NICE TO MEET HIM AT SCIENTIFIC UPDATE OPRD CONFERENCE IN PUNE INDIA DEC 5 2014. WEBSITE http://www.catalysisconsulting.co.uk/ Paul Murray Catalysis Consulting...
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Total synthesis of the proposed structure of Astakolactin……….Dr Corey Johnson
Originally posted on New Drug Approvals: picture credit…………Dr Corey johnson Astakolactin is a sesterpene from the Ionian Sea near Greece possessing considerable biological properties. Hence, that’s...
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Lycosperramine-R synthesis
Originally posted on Naturalproductman's Blog: Hiromitsu Takayama and co-workers from Chiba University have reported in Tetrahedron on the synthesis of lycosperramine R. Tetrahedron paper View original
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Synthetic applications of quintuple bonds?
Originally posted on Organic Chemistry Periodically: Wow. Wow, wow, wow. I was only vaguely aware that there were organometallic compounds containing quintuple bonds. They do exist, sure, but is there...
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A deacetonative Sonogashira coupling of aryl chlorides and propargyl alcohols
Originally posted on Organic Chemistry Periodically: While sp-sp2 couplings are now classics, whether using terminal alkynes, zinc, magnesium, boron or silicon alkynides, it is the first time I see a...
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MUSHROOM ALCOHOL
1-Octen-3-ol, octenol for short and also known as mushroom alcohol,[1] is a chemical that attracts biting insects such asmosquitoes. It is contained in human breath and sweat, and it was once believed...
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“Facile multi-decagram synthesis of methyl but-2-ynoate” B. Darses, I. N. Michaelides, D. J. Dixon, Org. Chem. Front. 2014, 1, 117-119 Facile multi-decagram synthesis of methyl but-2-ynoate Benjamin...
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Ni-Catalyzed Reduction of Inert C-O Bonds: A New Strategy for Using Aryl...
Ni-Catalyzed Reduction of Inert C-O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups Most synthetic chemists are used to employ aryl methyl ethers as directing groups....
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ORGANIC SPECTROSCOPY INTERNATIONAL……A blog to brush up spectroscopy fundamentals
Originally posted on New Drug Approvals: ORGANIC SPECTROSCOPY INTERNATIONAL…………A blog to brush up http://orgspectroscopyint.blogspot.in/2014/12/heavy-traffic-on-your-favorite.html...
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Many Little Pieces That Shan’t – Poem (after tragic tragic murder of kids in...
Originally posted on Darshana Varia Nadkarni's Blog: I can only imagine the deep deep anguish of parents of the children who lost their lives to terrorists in Pakistan. Here’s a poem dedicated to the...
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Seyferth-Gilbert Alkyne Synthesis
The Seyferth–Gilbert homologation is a chemical reaction of an aryl ketone 1 (or aldehyde) with dimethyl (diazomethyl)phosphonate 2 and potassium tert-butoxide to give substituted alkynes 3.[1][2]...
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Conversion of carbonyl compounds to alkynes: general overview and recent...
The preparation of alkynes from carbonyl compounds via a one-carbon homologation has become a very useful pathway for the synthesis of acetylenic compounds, both internal and terminal. This tutorial...
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